Sepsis and Emerging Infectious Diseases: Understanding the Connection

Sepsis and Emerging Infectious Diseases: Understanding the Connection

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Recorded On: 09/03/2020


Sepsis can be a final common pathway in disease progression irrespective of the pathogen causing infection. The role of emerging infectious diseases that can lead to sepsis will be discussed in this presentation. Sepsis should be considered in any emerging infectious disease response, including assessment for needed escalation of care and identification of at-risk patients. Medical countermeasures that address sepsis are, by definition, an important part of emerging infectious disease preparedness and include host-based diagnostics and improved patient management strategies. The historical role of coronaviruses, including SARS-CoV-2, and other emerging pathogens and their clinical implications with respect to sepsis will be reviewed.

Learning Objectives: 

At the end of the activity, the learner should be able to:

  • Define sepsis and understand the connection to all potential sources of infection, including coinfection and superinfection;
  • Describe the pathophysiology of sepsis and understand sepsis recognition in patients with an emerging infectious disease;
  • Recognize the importance of non-bacterial causes of sepsis, especially viral causes;
  • Review medical countermeasures for sepsis, including host-based diagnostics and improved patient management strategies, and their implications for practice;
  • Discuss the history and health security threats of coronavirus infections and other emerging infectious diseases.

Target Audience: 

Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.

Webinar Supporters:

Sepsis Alliance gratefully acknowledges the support provided for this webinar by the Sepsis Alliance Clinical Community sponsors.


Amesh Adalja, MD, FIDSA

Senior Scholar

Johns Hopkins University Center for Health Security

Dr. Adalja is a Senior Scholar at the Johns Hopkins University Center for Health Security. His work is focused on emerging infectious disease, pandemic preparedness, and biosecurity. Dr. Adalja has served on US government panels tasked with developing guidelines for the treatment of plague, botulism, and anthrax in mass casualty settings and the system of care for infectious disease emergencies. He is currently a member of the Infectious Diseases Society of America’s (IDSA) Precision Medicine working group; he previously served on their public health and diagnostics committees. He was formerly a member of the National Quality Forum’s Infectious Disease Standing Committee and the US Department of Health and Human Services’ National Disaster Medical System, with which he was deployed to Haiti after the 2010 earthquake; he was also selected for their mobile acute care strike team. Dr. Adalja’s expertise is frequently sought by international and national media.

Dr. Adalja completed 2 fellowships at the University of Pittsburgh—one in infectious diseases, for which he served as chief fellow, and one in critical care medicine. He completed a combined residency in internal medicine and emergency medicine at Allegheny General Hospital in Pittsburgh, where he served as chief resident and as a member of the infection control committee. He was a Clinical Assistant Professor at the University of Pittsburgh School of Medicine from 2010 through 2017 and is currently an adjunct assistant professor there.He is a graduate of the American University of the Caribbean School of Medicine, and he obtained a bachelor of science degree in industrial management from Carnegie Mellon University.

Provider approved by the California Board of Registered Nursing, Provider Number CEP17068 for 1.6 contact hours.

Other healthcare professionals will receive a certificate of attendance for 1.25 contact hours.

Medical Disclaimer

The information on or available through this site is intended for educational purposes only. Sepsis Alliance does not represent or guarantee that information on or available through this site is applicable to any specific patient’s care or treatment. The educational content on or available through this site does not constitute medical advice from a physician and is not to be used as a substitute for treatment or advice from a practicing physician or other healthcare professional. Sepsis Alliance recommends users consult their physician or healthcare professional regarding any questions about whether the information on or available through this site might apply to their individual treatment or care.

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