Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Sepsis remains a leading cause of death in U.S. hospitals and delayed or missed diagnosis continues to drive poor outcomes. Mortality increases by 4–9% for every hour treatment is delayed, yet missed infections, most commonly those that progress to sepsis, remain a leading source of diagnostic error. Rapid recognition and timely treatment can save up to 80% of patients with septic shock.
Advances in molecular diagnostics, host-response biomarkers, and AI-enabled decision support offer new opportunities to improve early sepsis recognition. Diagnostic stewardship, which includes ensuring appropriate test selection, interpretation, and action, is an essential but underutilized strategy to maximize the impact of these innovations.
The Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship convened clinicians, laboratorians, pharmacists, researchers, and healthcare leaders to address critical gaps in diagnostic accuracy and implementation. This virtual program highlights emerging technologies, real-world case examples, and practical strategies to strengthen diagnostic stewardship and improve patient outcomes.
Sepsis Alliance gratefully acknowledges the monetary support provided by Beckman Coulter for Day 1 of the Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship.

Thank You to the Sponsors of Day 2 of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship!
Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Sepsis Alliance designates this live activity for a maximum of 5.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Provider approved by the California Board of Registered Nursing, Provider Number CEP17068 for 6.6 contact hours.
Other healthcare professionals will receive a certificate of attendance for 5.75 contact hours.
All individuals in control of content for this activity disclosed no relevant financial relationships.
Medical Disclaimer
The information on or available through this site is intended for educational purposes only. Sepsis Alliance does not represent or guarantee that information on or available through this site is applicable to any specific patient’s care or treatment. The educational content on or available through this site does not constitute medical advice from a physician and is not to be used as a substitute for treatment or advice from a practicing physician or other healthcare professional. Sepsis Alliance recommends users consult their physician or healthcare professional regarding any questions about whether the information on or available through this site might apply to their individual treatment or care.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
This session was part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Steven Q. Simpson, MD
Professor of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine
University of Kansas
Steven Q. Simpson, MD is Professor of Medicine at the University of Kansas in the Division of Pulmonary, Critical Care, and Sleep Medicine, where he previously served as Division Director, Director of three ICUs, Chair of the Sepsis Team, and Chair of Multidisciplinary Critical Care. He has done research in all areas of severe sepsis from molecular and cellular mechanisms, to translational studies, to quality improvement studies.
He was a founder, in 2005, of the Midwest Critical Care Collaborative, a multidisciplinary and interprofessional collaborative effort to improve the quality of critical care services throughout the Midwest. In 2007, he initiated the Kansas Sepsis Project, a statewide program to improve severe sepsis care and outcomes throughout the state via continuing education both in sepsis and in quality improvement principles, and via inter-professional collaboration. He is currently heading a BCBS-sponsored sepsis collaborative among Kansas City metro area hospitals and is a contributing faculty member of the ongoing Surviving Sepsis Campaign collaboratives, leading the effort in the Midwest. He is a participant in the 2016 review and update of the Surviving Sepsis Campaign Guidelines.
Dr. Simpson was the North American co-chair of the International Single Day Point Prevalence Study for Severe Sepsis and Septic Shock (IMPRESS) in the fall of 2013. During his tenure at the University of New Mexico, he contributed to the discovery of a particular form of sepsis, the Hantavirus Pulmonary Syndrome, and published numerous papers on the clinical description, the hemodynamic description, and the approach to supportive care for patients with the syndrome, including extracorporeal hemodynamic and oxygenation support.
Dr. Simpson received his M.D. degree from the University of Kansas in 1983. He completed residency training in Internal Medicine at KU in 1986 and fellowship training in Pulmonary Diseases at Rush Medical College in 1989. He has been a faculty member at Rush Medical College, the University of New Mexico, and the University of Kansas. He is a regular reviewer for the journals Critical Care Medicine and CHEST, and he reviews on an ad hoc basis for Shock, the Journal of Intensive Care, JAMA, Virology, and Antiviral Therapy. He is the author of over 70 peer reviewed and invited manuscripts, book chapters, and web-based articles and presentations.
Dr. Simpson was the Third Eli Lilly and Company Distinguished Scholar in Critical Care Medicine, sponsored by the American College of Chest Physicians and the Chest Foundation for his work in reducing geographic disparities for severe sepsis care (the Kansas Sepsis Project). In 2013 he delivered the Roger C. Bone Memorial Lecture at the annual international meeting of the American College of Chest Physicians, describing the Kansas Sepsis Project. Dr. Bone was Dr. Simpson’s early career mentor and was the progenitor of the criteria used throughout the world to recognize severe sepsis.
No relevant financial relationships to disclose.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Rapid, precise diagnostics are essential to improving sepsis outcomes, but technology alone can’t close the gaps. This session embeds the CDC’s Diagnostic Stewardship recommendations into the value‑analysis process, so teams can more effectively select, implement, and evaluate sepsis diagnostic tools. A focused overview of the CDC framework, including test selection, specimen quality, timing, and rapid result pathways that support timely action will be presented, followed by how those principles are then translated into a value‑analysis approach that weighs sensitivity, specificity, time‑to‑result, operational fit, and the risks of false positives that can drive overtreatment.
Attendees will also explore strategies for aligning lab, nursing, infection prevention, and stewardship teams around practical specimen workflows. The session is highly actionable, offering a diagnostic‑evaluation checklist tied to CDC steps and a 30–90‑day pilot template with process and outcome KPIs. Real‑world examples, such as rapid molecular sepsis panels, procalcitonin‑guided algorithms, and blood‑culture optimization, will illustrate how diagnostic stewardship reduces costs, accelerates appropriate therapy, and strengthens antibiotic stewardship.
Learning Objectives:
At the end of this session, the learner should be able to:
- Apply the CDC’s diagnostic stewardship principles to evaluate sepsis diagnostics and their fit within local workflows.
- Design a short-cycle, diagnostic-focused value-analysis pilot that integrates diagnostic stewardship steps with lab and clinical workflows and links test performance to measurable episode-level outcomes
- Construct an evidence pack that aligns diagnostic decisions to antimicrobial stewardship goals, infection prevention priorities, and executive decision criteria.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Ruth Carrico, PhD, DNP, FNP-C, CIC, FSHEA, FNAP, FAAN
Senior Partner; Professor, Adjunct
Carrico & Ramirez, PLLC; University of Louisville School of Medicine, Division of Infectious Diseases
Ruth Carrico, PhD, DNP, APRN, FNP-C, CIC, FSHEA, FNAP, FAAN, is a senior consultant with Carrico & Ramirez, PLLC focused on infectious diseases, infection prevention and control, and vaccinology. She is also a Family Nurse Practitioner based in Louisville, Kentucky. In addition, Dr. Carrico is a Professor, adjunct faculty, with the University of Louisville School of Medicine, Division of Infectious Diseases. Dr. Carrico has received training specific for healthcare epidemiology at the Centers for Disease Control and Prevention (CDC) in conjunction with the Rollins School of Public Health at Emory University in Atlanta and the Society for Healthcare Epidemiology of America (SHEA).
Dr. Carrico has worked in the field of infectious diseases and infection control for more than thirty years. Her work in infection control began in 1994 when she assumed the position as Director of the Infection Control department at the University of Louisville Hospital. She quickly recognized this as an area of intense interest and began active collaboration, seeking mentoring from national and international experts. From 2005-2012, she served as Editor for the APIC Text of Infection Control and Epidemiology, was appointed to the National Biosurveillance Subcommittee (NBS) Advisory Committee to the Director, Centers for Disease Control and Prevention, and in 2010 became a SHEA Fellow. In 2011, Dr. Carrico was appointed by Secretary Sebelius (Health and Human Services), to the Healthcare Infection Control Practices Advisory Committee (HICPAC). In 2012, she was presented with the Carole DeMille Achievement Award by APIC, an honor for an Infection Preventionist. In 2013, Dr. Carrico began serving the National Foundation for Infectious Diseases as the Board’s Nurse Planner and in 2014 became a Robert Wood Johnson Foundation Executive Nurse Fellow alumna.
Dr. Carrico served as the 2016 President of the Certification Board of Infection Control and Epidemiology, Inc. (CBIC). In 2018, Dr. Carrico assumed the position of President of the Kentucky Nurses Association and in 2020 was recognized as a Distinguished Fellow in the National Academies of Practice. In October 2021, Dr. Carrico was inducted as a Fellow in the American Academy of Nursing, the highest honor in the nursing profession. Also in October 2021, Dr. Carrico assumed the role of Executive Director, then Senior Scientific Officer of the Norton Infectious Diseases Institute (NIDI) at Norton Healthcare in Louisville, Kentucky, where she supported the scientific and educational activities of the four Centers (Clinical Research, Education & Training, Global Health, Public Health) within the Institute until early 2023. During that time, she also led the CDC-funded Kentucky Infection Prevention (KYIP) Training Center, a broad educational program for infection preventionists and partners across the healthcare continuum. Following successful launch of the NIDI Centers and the KYIP Training Center, in 2023 Dr. Carrico moved to work as a full-time consultant with healthcare organizations, public health workers, providers, and industry partners sharing interests in addressing the challenges of infectious diseases prevention. Dr. Carrico serves on numerous advisory boards focused on vaccines and improving vaccination rates. She continues to conceptualize and implement novel immunization approaches including training and competence development for healthcare providers and healthcare workers, including an educational website supporting vaccination and international travel health (TH101.com). Dr. Carrico provides consultation and service as Medical Affairs lead for VaxCare, LLC [Orlando] and maintains a clinical practice focused on vaccines, vaccination, and immunization processes (Trifecta Medical Group, Louisville, KY).
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J. Hudson Garrett Jr., PhD, MSN, MPH, MBA, FNP-BC, CPHQ, PLNC, AS-BC, IP-BC, VA-BC™, CPPS, CDONA, CPXP, CIC, CER, LTC-CIP, CAIP, HACP, CHIPP-B, CMRP, CPHRM, CVAHP, CDIPC, FACDONA, FAAPM, FAOM, FRSPH, FNAP, FAPIC, FAHVAP, FSHEA, FIDSA, FACHE
Adjunct Assistant Professor of Medicine, Division of Infectious Diseases, Department of Medicine
University of Louisville School of Medicine
Dr. Hudson Garrett is an Adjunct Assistant Professor of Medicine in the Division of Infectious Diseases, Department of Medicine at the University of Louisville School of Medicine. He holds a Graduate Certificate in Infection Prevention and Infection Control from the University of South Florida. He has completed the Johns Hopkins Fellows Program in Hospital Epidemiology and Infection Control. He is a Fellow, the American Academy of Project Management, and a Senior Fellow and Ambassador of the Management and Strategy Institute. In 2019, he was inducted as a Distinguished Fellow and Practitioner in the National Academies of Practices. Dr. Garrett was recently selected as 1 of 20 healthcare leaders globally to participate in the 2021 13-month Global Patient Safety Fellowship with the Institute for Healthcare Improvement and is a graduate of the IHI Patient Safety Executive Development Program. Dr. Garrett has been awarded the Fellowship Designation by both the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America. He holds graduate certificates in healthcare leadership from both Cornell and the University of Notre Dame. He is a Fellow in the American College of Healthcare Executives, the Royal Society of Public Health, the Association of Professionals in Infection Control and Epidemiology, and the American College of the Association of Healthcare Value Analysis Professionals. He serves as the lead faculty member for the Medical Device Safety, Infection Control Specialist, and Advanced Medical Device Safety and Risk Management Certificate Programs for the AHVAP Certification Center.
He is a frequent international lecturer in the areas of infectious diseases, healthcare-associated infections, outbreak response and prevention, vascular access, patient safety, healthcare quality and risk management, medical device-related infections and outbreaks, endoscope safety, and infection prevention and control. He holds Board Certifications in Patient Safety, Healthcare Quality, Healthcare Risk Management, Legal Nurse Consulting, Medical and Clinical Affairs, Patient Experience, Vascular Access, Antibiotic Stewardship, Infection Control, Long-Term Care Infection Control, Dental Infection Control, Designated Infection Control Officer, Flexible Endoscope Reprocessing, Critical Care Fundamentals, Ambulatory Infection Prevention, Healthcare Value Analysis, and in Healthcare Management.
He has served on international and national organizational boards in the areas of healthcare environmental services, dental infection control, infection control, acute care infection control, post-acute care infection control, healthcare value analysis, infusion nursing, and vascular access. He has served on expert panels related to disinfection and sterilization with the United States Food and Drug Administration, Centers for Disease Control and Prevention, the Occupational Safety and Health Administration, and the Environmental Protection Agency, most notably serving on the FDA’s Panel and Working Group for Flexible Endoscope Reprocessing. Dr. Garrett led and completed the first FDA 522 Study on Duodenoscopes evaluating human factors elements of instructions for use and microbiological contamination of flexible duodenoscopes. He presented these results to the Food and Drug Administration, Centers for Disease Control and Prevention, and other clinical partner organizations globally. He is a member of the Network of Experts for the US Food and Drug Administration. He currently is the Chairperson for the new national Association of Perioperative Registered Nurses Infection Prevention National Task Force and serves as a member of the National Guidelines Advisory Board for AORN. Dr. Garrett has lectured around the world and provided testimony to government and regulatory agencies on a variety of topics related to infectious diseases and infection prevention and control.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
This session traces the evolution of computer‑assisted sepsis detection, from early predictive models to today’s advanced clinical decision support systems. Drawing on two decades of real‑world experience, the presenter will examine why high‑performing algorithms have not always led to better patient outcomes and unpacks the practical challenges that shape success, including workflow integration, clinician trust, alert fatigue, bias, and governance. Attendees will gain a stronger understanding of how these lessons are redefining what responsible, effective AI in clinical care must look like.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe the limitations of AI-based sepsis prediction models when applied in real-world clinical settings, including factors that affect clinical adoption and patient outcomes.
- Apply principles of decision-aware clinical decision support to evaluate AI-assisted sepsis tools within existing clinical workflows.
- Assess organizational, ethical, and governance considerations relevant to the implementation and oversight of AI-enabled sepsis decision support in healthcare systems.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Vitaly Herasevich, MD, PhD, MSc
Professor of Anesthesiology; Professor of Medicine in the Department of Anesthesiology and Perioperative Medicine
Division of Critical Care, Mayo Clinic - Rochester
Vitaly Herasevich, MD, PhD, MSc, is a Professor of Anesthesiology and a Professor of Medicine in the Department of Anesthesiology and Perioperative Medicine, Division of Critical Care at the Mayo Clinic, in Rochester, Minnesota. He has been involved in medical informatics for over 25 years, with a specific concentration on applied clinical informatics in critical care and the science of health care delivery.
Dr. Herasevich joined Mayo Clinic in 2006 and co-directed the Mayo Clinic Clinical Informatics in Intensive Care Laboratory. Dr. Herasevich's applied clinical informatics in critical care work included clinical data representation, ambient decision support, and alerting systems for early detection of critical syndromes and hospital-wide surveillance. He architected data warehouses in support of clinical decision-making quality and outcomes research. With longstanding interest in information security and more recent interest in computer vision, Dr. Herasevich has coauthored over 150 scientific articles and >span class="NormalTextRun SCXW247208915 BCX0">book “Health Information Evaluation Handbook” (now in the second edition).
Dr. Herasevich has a long mentorship record. In addition to being appointed with full faculty privileges in clinical research and artificial intelligence at Mayo Graduate School, he developed the Informatics Curriculum for Mayo Medical School, CCaTS, and the Master’s in Medical AI programs. Dr. Herasevich is principal investigator, co-investigator, and informatics expert for past and ongoing federal and industry-funded projects totaling more than $115 million in research support. Dr. Herasevich is Fellow of American College of Critical Care Medicine (FCCM), Fellow of HIMSS (FHIMSS), and President of Minnesota HIMSS Chapter.
No relevant financial relationships to disclose.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
This session explores how diagnostic stewardship can reshape sepsis care by highlighting real clinical scenarios where early decisions significantly influenced patient outcomes. Through case-based examples, attendees will examine how common practices may unintentionally lead to unnecessary interventions and patient harm. The session will emphasize the value of precise, high‑quality diagnostic reasoning and the role it plays in guiding safer, more effective care pathways. Attendees will also look at rapid diagnostic technologies that are transforming sepsis identification and enabling more targeted treatment. By connecting evidence, technology, and frontline decision‑making, the session equips learners with practical strategies to elevate diagnostic performance in time‑sensitive situations.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe overtreatment and its potential harms
- Explain the importance of diagnostic excellence
- Review rapid diagnosis tests for sepsis and how they impact patient outcomes
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Edward J. Septimus, MD, FIDSA, FACP, FSHEA
Senior Lecturer, Department of Population Medicine
Harvard Medical School
Ed Septimus, MD, FIDSA, FACP, FSHEA, received his medical degree from Baylor College of Medicine in Houston in 1972. He is board certified in both internal medicine and infectious diseases. after completing his postgraduate training in internal medicine and infectious diseases also at Baylor College of Medicine in Houston.
Dr. Septimus was Vice President of Research and Infectious Diseases at HCA Healthcare until 2018. Prior to HCA, he was the Medical Director of Infectious Diseases and Occupational Health for Memorial Hermann Healthcare System. He has served on the Board of Directors of the Infectious Diseases Society of America (IDSA) and was on the IDSA Antimicrobial Resistance Committee, the SHEA Antimicrobial Stewardship Committee, and the IDSA Quality Measurement Committee. He is now on the IDSA Sepsis Task Force. Dr. Septimus was chair of the Healthcare Safety Advisory Committee for the Texas Department of State Health Services from 2018-2021 and was the first recipient of the IDSA Watanakunakorn Clinician Award. He was also awarded the John S Dunn Sr. Outstanding Teacher Award. Until the end of 2021, Dr. Septimus was co-chair of the NQF Patient Safety Steering Committee. He is now vice chair of the NQF Consensus Standards Approval Committee and holds faculty positions as Adjunct Professor at Texas A&M College of Medicine, Senior Lecturer Department of Population Medicine Harvard Medical School, and as Adjunct Professor of Medicine Houston Methodist Research Institute/Weill Cornell. He has published over 140 articles and chapters.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Rapid diagnostics have dramatically shortened the time to identify sepsis, yet faster results do not always translate into faster treatment. This session explores how collaborative care models spanning the laboratory, clinicians, pharmacists, and stewardship teams can bridge the gap between diagnosis and action. Using real-world examples, participants will examine common system failures that delay therapy despite rapid diagnostic turnaround and learn practical strategies to overcome them. Attendees will leave with actionable communication frameworks and stewardship approaches that enable teams to work faster together, ensuring that sepsis diagnostics lead to timely, effective clinical decisions and improved patient outcomes.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe how collaborative workflows transform rapid sepsis diagnostic results into timely clinical action;
- Recognize common system failures that delay treatment despite fast diagnostic turnaround;
- Implement communication and stewardship strategies that improve the clinical impact of sepsis diagnostics.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Daniel A. Green, MD
Associate Professor of Pathology and Cell Biology
Columbia University Vagelos College of Physicians and Surgeons;
Daniel A. Green, MD, is an Associate Professor of Pathology and Cell Biology at Columbia University Vagelos College of Physicians and Surgeons and Co-Director of the Clinical Microbiology Laboratory at New York-Presbyterian/Columbia University Irving Medical Center. His work focuses on diagnostic innovation, clinical utility, and antimicrobial stewardship, with particular emphasis on ensuring that microbiology diagnostics translate into timely, actionable improvements in patient care. Dr. Green has published extensively on the clinical impact of rapid diagnostics, diagnostic stewardship, and infectious disease outcomes, and serves on the editorial boards of the Journal of Clinical Microbiology and ASM Case Reports. He is Director of Columbia’s ACGME-accredited Clinical Microbiology Fellowship Program and is actively involved in national educational and professional society initiatives.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Daniel A. Green, MD
Associate Professor of Pathology and Cell Biology
Columbia University Vagelos College of Physicians and Surgeons;
Daniel A. Green, MD, is an Associate Professor of Pathology and Cell Biology at Columbia University Vagelos College of Physicians and Surgeons and Co-Director of the Clinical Microbiology Laboratory at New York-Presbyterian/Columbia University Irving Medical Center. His work focuses on diagnostic innovation, clinical utility, and antimicrobial stewardship, with particular emphasis on ensuring that microbiology diagnostics translate into timely, actionable improvements in patient care. Dr. Green has published extensively on the clinical impact of rapid diagnostics, diagnostic stewardship, and infectious disease outcomes, and serves on the editorial boards of the Journal of Clinical Microbiology and ASM Case Reports. He is Director of Columbia’s ACGME-accredited Clinical Microbiology Fellowship Program and is actively involved in national educational and professional society initiatives.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Accurate diagnosis of sepsis remains a critical yet complex challenge in modern clinical practice. False-negative results may delay life-saving therapy, while contaminated cultures and misleading molecular findings can prompt unnecessary antimicrobial exposure, prolonged hospitalization, and increased healthcare costs.
This session will examine the diagnostic limitations and vulnerabilities of current sepsis testing modalities, including blood cultures and rapid molecular platforms. Participants will review common pitfalls across the diagnostic workflow from specimen collection to interpretation, and explore practical, evidence-based strategies to distinguish true infection from contamination. Emphasis will be placed on diagnostic stewardship, antimicrobial decision-making, and systems-based approaches to improving accuracy and patient safety in suspected sepsis.
Learning Objectives:
At the end of this session, the learner should be able to:
- Identify common causes of false-negative and false-positive (contaminant) results in sepsis diagnostic testing, including blood cultures and rapid molecular assays;
- Differentiate true bloodstream infection from specimen contamination using clinical, microbiologic, and laboratory data;
- Evaluate pre-analytic, analytic, and post-analytic factors that contribute to diagnostic inaccuracies in sepsis testing;
- Apply evidence-based strategies to optimize blood culture collection, antimicrobial timing, and diagnostic stewardship to reduce errors and improve patient outcomes;
- Integrate principles of antimicrobial stewardship into clinical decision-making when confronted with discordant or ambiguous sepsis test results.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Cindy Hou, DO, MA, MBA, CIC, CPHQ, FACOI, FACP, FIDSA, FAPIC
Infection Control Officer and Medical Director of Research
Jefferson Health – New Jersey
Cindy Hou, DO, MA, MBA, CIC, CPHQ, FACOI, FACP, FIDSA, FAPIC, is the Infection Control Officer and Medical Director of Research for Jefferson Health – New Jersey and an Infectious Diseases specialist. She has expertise in sepsis, antibiotic stewardship, infection control, patient safety, clinical quality, equity, and language access.
Dr. Hou is the Chief Medical Officer of Sepsis Alliance and a member of its Board of Directors. She earned her M.B.A. and M.A. from Boston University, a D.O. from the University of New England College of Osteopathic Medicine, and her B.S. from Yale University.
Dr. Hou is the principal investigator for an Office of Minority Health grant to reduce inequities in those with limited English proficiency. She is the co-editor of the book, “COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes.”
Dr. Hou has a Certification in Infection Prevention and Control, is a Certified Professional in Healthcare Quality, and is a Certified Professional in Patient Safety. Dr. Hou is a Fellow of the American College of Osteopathic Internists, American College of Physicians, Infectious Diseases Society of America, and Association for Professionals in Infection Control and Epidemiology.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Accurate and timely sepsis diagnosis depends on far more than technology; it relies on the people, processes, and communication that guide a specimen from bedside to benchtop. In this sponsored session, we follow the complete journey of a blood culture and examine how each touchpoint contributes to (or undermines) diagnostic accuracy. Using a dual perspective approach from both nursing and the clinical microbiology laboratory, we explore where breakdowns commonly occur, such as suboptimal fill volumes, contamination events, timing challenges, and communication gaps, and how these failures impact downstream identification, rapid testing, and ultimately, patient outcomes.
Participants will gain insight into high impact front end practices, the laboratory’s data driven stewardship priorities, and the shared metrics (like contamination rates and fill volumes) that meaningfully improve performance when reviewed collaboratively. We also highlight practical strategies for closing the loop between teams, including joint education, feedback mechanisms, and tools that make quality data visible and actionable at the unit level.
Attendees will leave with a clearer understanding of how nursing and laboratory partnerships can elevate diagnostic stewardship efforts, ensuring that rapid diagnostics are not only available, but truly trusted, interpreted correctly, and used to guide timely, appropriate therapy in sepsis care.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Kayla Kirby, RN, MLS, ASCP
Global Medical Science Liaison
Waters Advanced Diagnostics
Kayla Kirby, RN, MLS, ASCP, is a global medical science liaison for BD diagnostic solutions. She is also licensed as a registered nurse in Indiana and certified as a medical laboratory scientist. Her areas of experience include clinical microbiology laboratory work, and critical care nursing. At BD, Kayla is focused on scientific education, training, and engagement for the microbiology and molecular portfolios. Kayla’s primary focuses include the BACTEC™ blood culture system and the BD MAX™ enteric and healthcare-associated infection assays.
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Kayla Van Benten, BS, M(ASCP)
Sr. Manager, Medical Affairs
Waters Advanced Diagnostics
Kayla Van Benten, BS, M(ASCP), is a Senior Manager of Medical Affairs for Waters Advanced Diagnostics and is certified as a Medical Technologist. She brings more than a decade of experience in the clinical microbiology laboratory, including six years in laboratory leadership and management roles. At Waters, Kayla leads the global post-market evidence generation strategy for the microbiology portfolio and oversees the worldwide Medical Science Liaison team. Her professional interests include ID/AST, antimicrobial resistance, and antimicrobial stewardship, with a particular focus on connecting scientific evidence with strategic decision making to support improved patient care.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Timely and accurate diagnosis of sepsis is essential to improving outcomes, yet resource-limited settings face unique challenges, including limited laboratory capacity, delayed testing, workforce constraints, and competing clinical priorities.
This session will examine current and emerging approaches to sepsis diagnostics with an emphasis on diagnostic stewardship in low-resource and under-resourced environments. Participants will explore practical strategies for optimizing the use of available diagnostic tools, such as clinical criteria, basic laboratory tests, microbiology, and point-of-care technologies, while minimizing unnecessary testing and delays in treatment. Context-appropriate algorithms, implementation considerations, and examples from global and rural health settings will also be highlighted. Emphasis will be placed on balancing early sepsis recognition, antimicrobial stewardship, cost-effectiveness, and equitable access to care.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe key challenges and limitations affecting sepsis diagnosis in resource-limited settings.
- Apply principles of diagnostic stewardship to optimize sepsis evaluation using available clinical and laboratory resources;
- Compare the utility of clinical assessment, basic laboratory testing, microbiology, and point-of-care diagnostics for sepsis in low-resource environments.
- Integrate diagnostic strategies that support timely treatment while minimizing unnecessary testing and inappropriate antimicrobial use.
- Identify practical, scalable approaches to improving sepsis diagnostic pathways in resource-constrained health systems.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Michael McCurdy, MD
Clinical Professor of Pulmonary and Critical Care Medicine and Emergency Medicine
University School of Maryland School of Medicine
Michael McCurdy, MD, is a triple-board-certified critical care physician who has used his extensive clinical and research experience to focus on creating, developing, and deploying novel solutions to complex medical problems encountered in the inpatient, outpatient, austere, and military environments. A clinical professor of Pulmonary and Critical Care Medicine and Emergency Medicine at The University of Maryland School of Medicine, Dr. McCurdy has authored over 130 peer-reviewed manuscripts. His clinical research primarily focuses on novel ways to identify and resuscitate sepsis and other shock states, improve acute medical care in austere environments, and provide telemedical ultrasound support to remote clinicians. His work has led to multiple inventions to assist with bedside resuscitation efforts. He serves as an advisor or board member for several companies and nonprofit organizations.
Dr. McCurdy remains involved with Nereus Medical Solutions, which delivers critical care in various austere environments around the globe. While he enjoyed serving as the lone physician providing medical support for a National Geographic around-the-world trip to many of the globe’s most remote regions, hehas focused the bulk of his international efforts on St. Luke’s Hospital in Port-au-Prince, Haiti. His multi-year efforts there centered on educating Haitian physicians to conduct clinical research for the purpose of establishing a long-term, sustainable medical infrastructure that seamlessly integrates low-cost technology and high-quality education and patient care. His hope is that his group’s work will serve generations of Haitians while also providing a framework for the creation of similar sustainable medical care in other resource-limited countries.
Dr. McCurdy previously served as the Chief Medical Officer of BOA Biomedical, utilizing a DARPA-funded pan-pathogen-binding protein developed at Harvard University’s Wyss Institute to enable rapid pathogen identification and clearance. He now serves as the CMO of Clairyon, a University of California San Diego-based AI company focused on deploying: inpatient and outpatient sepsis predictive analytics tools that ingest and process multimodal data sources (e.g., EHR, wearables, symptom assessment tools), automated inpatient quality assessment and reporting, and a generative AI mobile chatbot to streamline the management of illness and predict the development of outpatient clinical decompensation, particularly from sepsis.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
This session was part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Steven Q. Simpson, MD
Professor of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine
University of Kansas
Steven Q. Simpson, MD is Professor of Medicine at the University of Kansas in the Division of Pulmonary, Critical Care, and Sleep Medicine, where he previously served as Division Director, Director of three ICUs, Chair of the Sepsis Team, and Chair of Multidisciplinary Critical Care. He has done research in all areas of severe sepsis from molecular and cellular mechanisms, to translational studies, to quality improvement studies.
He was a founder, in 2005, of the Midwest Critical Care Collaborative, a multidisciplinary and interprofessional collaborative effort to improve the quality of critical care services throughout the Midwest. In 2007, he initiated the Kansas Sepsis Project, a statewide program to improve severe sepsis care and outcomes throughout the state via continuing education both in sepsis and in quality improvement principles, and via inter-professional collaboration. He is currently heading a BCBS-sponsored sepsis collaborative among Kansas City metro area hospitals and is a contributing faculty member of the ongoing Surviving Sepsis Campaign collaboratives, leading the effort in the Midwest. He is a participant in the 2016 review and update of the Surviving Sepsis Campaign Guidelines.
Dr. Simpson was the North American co-chair of the International Single Day Point Prevalence Study for Severe Sepsis and Septic Shock (IMPRESS) in the fall of 2013. During his tenure at the University of New Mexico, he contributed to the discovery of a particular form of sepsis, the Hantavirus Pulmonary Syndrome, and published numerous papers on the clinical description, the hemodynamic description, and the approach to supportive care for patients with the syndrome, including extracorporeal hemodynamic and oxygenation support.
Dr. Simpson received his M.D. degree from the University of Kansas in 1983. He completed residency training in Internal Medicine at KU in 1986 and fellowship training in Pulmonary Diseases at Rush Medical College in 1989. He has been a faculty member at Rush Medical College, the University of New Mexico, and the University of Kansas. He is a regular reviewer for the journals Critical Care Medicine and CHEST, and he reviews on an ad hoc basis for Shock, the Journal of Intensive Care, JAMA, Virology, and Antiviral Therapy. He is the author of over 70 peer reviewed and invited manuscripts, book chapters, and web-based articles and presentations.
Dr. Simpson was the Third Eli Lilly and Company Distinguished Scholar in Critical Care Medicine, sponsored by the American College of Chest Physicians and the Chest Foundation for his work in reducing geographic disparities for severe sepsis care (the Kansas Sepsis Project). In 2013 he delivered the Roger C. Bone Memorial Lecture at the annual international meeting of the American College of Chest Physicians, describing the Kansas Sepsis Project. Dr. Bone was Dr. Simpson’s early career mentor and was the progenitor of the criteria used throughout the world to recognize severe sepsis.
No relevant financial relationships to disclose.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Rapid, precise diagnostics are essential to improving sepsis outcomes, but technology alone can’t close the gaps. This session embeds the CDC’s Diagnostic Stewardship recommendations into the value‑analysis process, so teams can more effectively select, implement, and evaluate sepsis diagnostic tools. A focused overview of the CDC framework, including test selection, specimen quality, timing, and rapid result pathways that support timely action will be presented, followed by how those principles are then translated into a value‑analysis approach that weighs sensitivity, specificity, time‑to‑result, operational fit, and the risks of false positives that can drive overtreatment.
Attendees will also explore strategies for aligning lab, nursing, infection prevention, and stewardship teams around practical specimen workflows. The session is highly actionable, offering a diagnostic‑evaluation checklist tied to CDC steps and a 30–90‑day pilot template with process and outcome KPIs. Real‑world examples, such as rapid molecular sepsis panels, procalcitonin‑guided algorithms, and blood‑culture optimization, will illustrate how diagnostic stewardship reduces costs, accelerates appropriate therapy, and strengthens antibiotic stewardship.
Learning Objectives:
At the end of this session, the learner should be able to:
- Apply the CDC’s diagnostic stewardship principles to evaluate sepsis diagnostics and their fit within local workflows.
- Design a short-cycle, diagnostic-focused value-analysis pilot that integrates diagnostic stewardship steps with lab and clinical workflows and links test performance to measurable episode-level outcomes
- Construct an evidence pack that aligns diagnostic decisions to antimicrobial stewardship goals, infection prevention priorities, and executive decision criteria.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Ruth Carrico, PhD, DNP, FNP-C, CIC, FSHEA, FNAP, FAAN
Senior Partner; Professor, Adjunct
Carrico & Ramirez, PLLC; University of Louisville School of Medicine, Division of Infectious Diseases
Ruth Carrico, PhD, DNP, APRN, FNP-C, CIC, FSHEA, FNAP, FAAN, is a senior consultant with Carrico & Ramirez, PLLC focused on infectious diseases, infection prevention and control, and vaccinology. She is also a Family Nurse Practitioner based in Louisville, Kentucky. In addition, Dr. Carrico is a Professor, adjunct faculty, with the University of Louisville School of Medicine, Division of Infectious Diseases. Dr. Carrico has received training specific for healthcare epidemiology at the Centers for Disease Control and Prevention (CDC) in conjunction with the Rollins School of Public Health at Emory University in Atlanta and the Society for Healthcare Epidemiology of America (SHEA).
Dr. Carrico has worked in the field of infectious diseases and infection control for more than thirty years. Her work in infection control began in 1994 when she assumed the position as Director of the Infection Control department at the University of Louisville Hospital. She quickly recognized this as an area of intense interest and began active collaboration, seeking mentoring from national and international experts. From 2005-2012, she served as Editor for the APIC Text of Infection Control and Epidemiology, was appointed to the National Biosurveillance Subcommittee (NBS) Advisory Committee to the Director, Centers for Disease Control and Prevention, and in 2010 became a SHEA Fellow. In 2011, Dr. Carrico was appointed by Secretary Sebelius (Health and Human Services), to the Healthcare Infection Control Practices Advisory Committee (HICPAC). In 2012, she was presented with the Carole DeMille Achievement Award by APIC, an honor for an Infection Preventionist. In 2013, Dr. Carrico began serving the National Foundation for Infectious Diseases as the Board’s Nurse Planner and in 2014 became a Robert Wood Johnson Foundation Executive Nurse Fellow alumna.
Dr. Carrico served as the 2016 President of the Certification Board of Infection Control and Epidemiology, Inc. (CBIC). In 2018, Dr. Carrico assumed the position of President of the Kentucky Nurses Association and in 2020 was recognized as a Distinguished Fellow in the National Academies of Practice. In October 2021, Dr. Carrico was inducted as a Fellow in the American Academy of Nursing, the highest honor in the nursing profession. Also in October 2021, Dr. Carrico assumed the role of Executive Director, then Senior Scientific Officer of the Norton Infectious Diseases Institute (NIDI) at Norton Healthcare in Louisville, Kentucky, where she supported the scientific and educational activities of the four Centers (Clinical Research, Education & Training, Global Health, Public Health) within the Institute until early 2023. During that time, she also led the CDC-funded Kentucky Infection Prevention (KYIP) Training Center, a broad educational program for infection preventionists and partners across the healthcare continuum. Following successful launch of the NIDI Centers and the KYIP Training Center, in 2023 Dr. Carrico moved to work as a full-time consultant with healthcare organizations, public health workers, providers, and industry partners sharing interests in addressing the challenges of infectious diseases prevention. Dr. Carrico serves on numerous advisory boards focused on vaccines and improving vaccination rates. She continues to conceptualize and implement novel immunization approaches including training and competence development for healthcare providers and healthcare workers, including an educational website supporting vaccination and international travel health (TH101.com). Dr. Carrico provides consultation and service as Medical Affairs lead for VaxCare, LLC [Orlando] and maintains a clinical practice focused on vaccines, vaccination, and immunization processes (Trifecta Medical Group, Louisville, KY).
$i++ ?>J. Hudson Garrett Jr., PhD, MSN, MPH, MBA, FNP-BC, CPHQ, PLNC, AS-BC, IP-BC, VA-BC™, CPPS, CDONA, CPXP, CIC, CER, LTC-CIP, CAIP, HACP, CHIPP-B, CMRP, CPHRM, CVAHP, CDIPC, FACDONA, FAAPM, FAOM, FRSPH, FNAP, FAPIC, FAHVAP, FSHEA, FIDSA, FACHE
Adjunct Assistant Professor of Medicine, Division of Infectious Diseases, Department of Medicine
University of Louisville School of Medicine
Dr. Hudson Garrett is an Adjunct Assistant Professor of Medicine in the Division of Infectious Diseases, Department of Medicine at the University of Louisville School of Medicine. He holds a Graduate Certificate in Infection Prevention and Infection Control from the University of South Florida. He has completed the Johns Hopkins Fellows Program in Hospital Epidemiology and Infection Control. He is a Fellow, the American Academy of Project Management, and a Senior Fellow and Ambassador of the Management and Strategy Institute. In 2019, he was inducted as a Distinguished Fellow and Practitioner in the National Academies of Practices. Dr. Garrett was recently selected as 1 of 20 healthcare leaders globally to participate in the 2021 13-month Global Patient Safety Fellowship with the Institute for Healthcare Improvement and is a graduate of the IHI Patient Safety Executive Development Program. Dr. Garrett has been awarded the Fellowship Designation by both the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America. He holds graduate certificates in healthcare leadership from both Cornell and the University of Notre Dame. He is a Fellow in the American College of Healthcare Executives, the Royal Society of Public Health, the Association of Professionals in Infection Control and Epidemiology, and the American College of the Association of Healthcare Value Analysis Professionals. He serves as the lead faculty member for the Medical Device Safety, Infection Control Specialist, and Advanced Medical Device Safety and Risk Management Certificate Programs for the AHVAP Certification Center.
He is a frequent international lecturer in the areas of infectious diseases, healthcare-associated infections, outbreak response and prevention, vascular access, patient safety, healthcare quality and risk management, medical device-related infections and outbreaks, endoscope safety, and infection prevention and control. He holds Board Certifications in Patient Safety, Healthcare Quality, Healthcare Risk Management, Legal Nurse Consulting, Medical and Clinical Affairs, Patient Experience, Vascular Access, Antibiotic Stewardship, Infection Control, Long-Term Care Infection Control, Dental Infection Control, Designated Infection Control Officer, Flexible Endoscope Reprocessing, Critical Care Fundamentals, Ambulatory Infection Prevention, Healthcare Value Analysis, and in Healthcare Management.
He has served on international and national organizational boards in the areas of healthcare environmental services, dental infection control, infection control, acute care infection control, post-acute care infection control, healthcare value analysis, infusion nursing, and vascular access. He has served on expert panels related to disinfection and sterilization with the United States Food and Drug Administration, Centers for Disease Control and Prevention, the Occupational Safety and Health Administration, and the Environmental Protection Agency, most notably serving on the FDA’s Panel and Working Group for Flexible Endoscope Reprocessing. Dr. Garrett led and completed the first FDA 522 Study on Duodenoscopes evaluating human factors elements of instructions for use and microbiological contamination of flexible duodenoscopes. He presented these results to the Food and Drug Administration, Centers for Disease Control and Prevention, and other clinical partner organizations globally. He is a member of the Network of Experts for the US Food and Drug Administration. He currently is the Chairperson for the new national Association of Perioperative Registered Nurses Infection Prevention National Task Force and serves as a member of the National Guidelines Advisory Board for AORN. Dr. Garrett has lectured around the world and provided testimony to government and regulatory agencies on a variety of topics related to infectious diseases and infection prevention and control.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
This session traces the evolution of computer‑assisted sepsis detection, from early predictive models to today’s advanced clinical decision support systems. Drawing on two decades of real‑world experience, the presenter will examine why high‑performing algorithms have not always led to better patient outcomes and unpacks the practical challenges that shape success, including workflow integration, clinician trust, alert fatigue, bias, and governance. Attendees will gain a stronger understanding of how these lessons are redefining what responsible, effective AI in clinical care must look like.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe the limitations of AI-based sepsis prediction models when applied in real-world clinical settings, including factors that affect clinical adoption and patient outcomes.
- Apply principles of decision-aware clinical decision support to evaluate AI-assisted sepsis tools within existing clinical workflows.
- Assess organizational, ethical, and governance considerations relevant to the implementation and oversight of AI-enabled sepsis decision support in healthcare systems.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Vitaly Herasevich, MD, PhD, MSc
Professor of Anesthesiology; Professor of Medicine in the Department of Anesthesiology and Perioperative Medicine
Division of Critical Care, Mayo Clinic - Rochester
Vitaly Herasevich, MD, PhD, MSc, is a Professor of Anesthesiology and a Professor of Medicine in the Department of Anesthesiology and Perioperative Medicine, Division of Critical Care at the Mayo Clinic, in Rochester, Minnesota. He has been involved in medical informatics for over 25 years, with a specific concentration on applied clinical informatics in critical care and the science of health care delivery.
Dr. Herasevich joined Mayo Clinic in 2006 and co-directed the Mayo Clinic Clinical Informatics in Intensive Care Laboratory. Dr. Herasevich's applied clinical informatics in critical care work included clinical data representation, ambient decision support, and alerting systems for early detection of critical syndromes and hospital-wide surveillance. He architected data warehouses in support of clinical decision-making quality and outcomes research. With longstanding interest in information security and more recent interest in computer vision, Dr. Herasevich has coauthored over 150 scientific articles and >span class="NormalTextRun SCXW247208915 BCX0">book “Health Information Evaluation Handbook” (now in the second edition).
Dr. Herasevich has a long mentorship record. In addition to being appointed with full faculty privileges in clinical research and artificial intelligence at Mayo Graduate School, he developed the Informatics Curriculum for Mayo Medical School, CCaTS, and the Master’s in Medical AI programs. Dr. Herasevich is principal investigator, co-investigator, and informatics expert for past and ongoing federal and industry-funded projects totaling more than $115 million in research support. Dr. Herasevich is Fellow of American College of Critical Care Medicine (FCCM), Fellow of HIMSS (FHIMSS), and President of Minnesota HIMSS Chapter.
No relevant financial relationships to disclose.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
This session explores how diagnostic stewardship can reshape sepsis care by highlighting real clinical scenarios where early decisions significantly influenced patient outcomes. Through case-based examples, attendees will examine how common practices may unintentionally lead to unnecessary interventions and patient harm. The session will emphasize the value of precise, high‑quality diagnostic reasoning and the role it plays in guiding safer, more effective care pathways. Attendees will also look at rapid diagnostic technologies that are transforming sepsis identification and enabling more targeted treatment. By connecting evidence, technology, and frontline decision‑making, the session equips learners with practical strategies to elevate diagnostic performance in time‑sensitive situations.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe overtreatment and its potential harms
- Explain the importance of diagnostic excellence
- Review rapid diagnosis tests for sepsis and how they impact patient outcomes
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Edward J. Septimus, MD, FIDSA, FACP, FSHEA
Senior Lecturer, Department of Population Medicine
Harvard Medical School
Ed Septimus, MD, FIDSA, FACP, FSHEA, received his medical degree from Baylor College of Medicine in Houston in 1972. He is board certified in both internal medicine and infectious diseases. after completing his postgraduate training in internal medicine and infectious diseases also at Baylor College of Medicine in Houston.
Dr. Septimus was Vice President of Research and Infectious Diseases at HCA Healthcare until 2018. Prior to HCA, he was the Medical Director of Infectious Diseases and Occupational Health for Memorial Hermann Healthcare System. He has served on the Board of Directors of the Infectious Diseases Society of America (IDSA) and was on the IDSA Antimicrobial Resistance Committee, the SHEA Antimicrobial Stewardship Committee, and the IDSA Quality Measurement Committee. He is now on the IDSA Sepsis Task Force. Dr. Septimus was chair of the Healthcare Safety Advisory Committee for the Texas Department of State Health Services from 2018-2021 and was the first recipient of the IDSA Watanakunakorn Clinician Award. He was also awarded the John S Dunn Sr. Outstanding Teacher Award. Until the end of 2021, Dr. Septimus was co-chair of the NQF Patient Safety Steering Committee. He is now vice chair of the NQF Consensus Standards Approval Committee and holds faculty positions as Adjunct Professor at Texas A&M College of Medicine, Senior Lecturer Department of Population Medicine Harvard Medical School, and as Adjunct Professor of Medicine Houston Methodist Research Institute/Weill Cornell. He has published over 140 articles and chapters.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Rapid diagnostics have dramatically shortened the time to identify sepsis, yet faster results do not always translate into faster treatment. This session explores how collaborative care models spanning the laboratory, clinicians, pharmacists, and stewardship teams can bridge the gap between diagnosis and action. Using real-world examples, participants will examine common system failures that delay therapy despite rapid diagnostic turnaround and learn practical strategies to overcome them. Attendees will leave with actionable communication frameworks and stewardship approaches that enable teams to work faster together, ensuring that sepsis diagnostics lead to timely, effective clinical decisions and improved patient outcomes.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe how collaborative workflows transform rapid sepsis diagnostic results into timely clinical action;
- Recognize common system failures that delay treatment despite fast diagnostic turnaround;
- Implement communication and stewardship strategies that improve the clinical impact of sepsis diagnostics.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Daniel A. Green, MD
Associate Professor of Pathology and Cell Biology
Columbia University Vagelos College of Physicians and Surgeons;
Daniel A. Green, MD, is an Associate Professor of Pathology and Cell Biology at Columbia University Vagelos College of Physicians and Surgeons and Co-Director of the Clinical Microbiology Laboratory at New York-Presbyterian/Columbia University Irving Medical Center. His work focuses on diagnostic innovation, clinical utility, and antimicrobial stewardship, with particular emphasis on ensuring that microbiology diagnostics translate into timely, actionable improvements in patient care. Dr. Green has published extensively on the clinical impact of rapid diagnostics, diagnostic stewardship, and infectious disease outcomes, and serves on the editorial boards of the Journal of Clinical Microbiology and ASM Case Reports. He is Director of Columbia’s ACGME-accredited Clinical Microbiology Fellowship Program and is actively involved in national educational and professional society initiatives.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Daniel A. Green, MD
Associate Professor of Pathology and Cell Biology
Columbia University Vagelos College of Physicians and Surgeons;
Daniel A. Green, MD, is an Associate Professor of Pathology and Cell Biology at Columbia University Vagelos College of Physicians and Surgeons and Co-Director of the Clinical Microbiology Laboratory at New York-Presbyterian/Columbia University Irving Medical Center. His work focuses on diagnostic innovation, clinical utility, and antimicrobial stewardship, with particular emphasis on ensuring that microbiology diagnostics translate into timely, actionable improvements in patient care. Dr. Green has published extensively on the clinical impact of rapid diagnostics, diagnostic stewardship, and infectious disease outcomes, and serves on the editorial boards of the Journal of Clinical Microbiology and ASM Case Reports. He is Director of Columbia’s ACGME-accredited Clinical Microbiology Fellowship Program and is actively involved in national educational and professional society initiatives.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Accurate diagnosis of sepsis remains a critical yet complex challenge in modern clinical practice. False-negative results may delay life-saving therapy, while contaminated cultures and misleading molecular findings can prompt unnecessary antimicrobial exposure, prolonged hospitalization, and increased healthcare costs.
This session will examine the diagnostic limitations and vulnerabilities of current sepsis testing modalities, including blood cultures and rapid molecular platforms. Participants will review common pitfalls across the diagnostic workflow from specimen collection to interpretation, and explore practical, evidence-based strategies to distinguish true infection from contamination. Emphasis will be placed on diagnostic stewardship, antimicrobial decision-making, and systems-based approaches to improving accuracy and patient safety in suspected sepsis.
Learning Objectives:
At the end of this session, the learner should be able to:
- Identify common causes of false-negative and false-positive (contaminant) results in sepsis diagnostic testing, including blood cultures and rapid molecular assays;
- Differentiate true bloodstream infection from specimen contamination using clinical, microbiologic, and laboratory data;
- Evaluate pre-analytic, analytic, and post-analytic factors that contribute to diagnostic inaccuracies in sepsis testing;
- Apply evidence-based strategies to optimize blood culture collection, antimicrobial timing, and diagnostic stewardship to reduce errors and improve patient outcomes;
- Integrate principles of antimicrobial stewardship into clinical decision-making when confronted with discordant or ambiguous sepsis test results.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Cindy Hou, DO, MA, MBA, CIC, CPHQ, FACOI, FACP, FIDSA, FAPIC
Infection Control Officer and Medical Director of Research
Jefferson Health – New Jersey
Cindy Hou, DO, MA, MBA, CIC, CPHQ, FACOI, FACP, FIDSA, FAPIC, is the Infection Control Officer and Medical Director of Research for Jefferson Health – New Jersey and an Infectious Diseases specialist. She has expertise in sepsis, antibiotic stewardship, infection control, patient safety, clinical quality, equity, and language access.
Dr. Hou is the Chief Medical Officer of Sepsis Alliance and a member of its Board of Directors. She earned her M.B.A. and M.A. from Boston University, a D.O. from the University of New England College of Osteopathic Medicine, and her B.S. from Yale University.
Dr. Hou is the principal investigator for an Office of Minority Health grant to reduce inequities in those with limited English proficiency. She is the co-editor of the book, “COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes.”
Dr. Hou has a Certification in Infection Prevention and Control, is a Certified Professional in Healthcare Quality, and is a Certified Professional in Patient Safety. Dr. Hou is a Fellow of the American College of Osteopathic Internists, American College of Physicians, Infectious Diseases Society of America, and Association for Professionals in Infection Control and Epidemiology.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Accurate and timely sepsis diagnosis depends on far more than technology; it relies on the people, processes, and communication that guide a specimen from bedside to benchtop. In this sponsored session, we follow the complete journey of a blood culture and examine how each touchpoint contributes to (or undermines) diagnostic accuracy. Using a dual perspective approach from both nursing and the clinical microbiology laboratory, we explore where breakdowns commonly occur, such as suboptimal fill volumes, contamination events, timing challenges, and communication gaps, and how these failures impact downstream identification, rapid testing, and ultimately, patient outcomes.
Participants will gain insight into high impact front end practices, the laboratory’s data driven stewardship priorities, and the shared metrics (like contamination rates and fill volumes) that meaningfully improve performance when reviewed collaboratively. We also highlight practical strategies for closing the loop between teams, including joint education, feedback mechanisms, and tools that make quality data visible and actionable at the unit level.
Attendees will leave with a clearer understanding of how nursing and laboratory partnerships can elevate diagnostic stewardship efforts, ensuring that rapid diagnostics are not only available, but truly trusted, interpreted correctly, and used to guide timely, appropriate therapy in sepsis care.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Kayla Kirby, RN, MLS, ASCP
Global Medical Science Liaison
Waters Advanced Diagnostics
Kayla Kirby, RN, MLS, ASCP, is a global medical science liaison for BD diagnostic solutions. She is also licensed as a registered nurse in Indiana and certified as a medical laboratory scientist. Her areas of experience include clinical microbiology laboratory work, and critical care nursing. At BD, Kayla is focused on scientific education, training, and engagement for the microbiology and molecular portfolios. Kayla’s primary focuses include the BACTEC™ blood culture system and the BD MAX™ enteric and healthcare-associated infection assays.
$i++ ?>Kayla Van Benten, BS, M(ASCP)
Sr. Manager, Medical Affairs
Waters Advanced Diagnostics
Kayla Van Benten, BS, M(ASCP), is a Senior Manager of Medical Affairs for Waters Advanced Diagnostics and is certified as a Medical Technologist. She brings more than a decade of experience in the clinical microbiology laboratory, including six years in laboratory leadership and management roles. At Waters, Kayla leads the global post-market evidence generation strategy for the microbiology portfolio and oversees the worldwide Medical Science Liaison team. Her professional interests include ID/AST, antimicrobial resistance, and antimicrobial stewardship, with a particular focus on connecting scientific evidence with strategic decision making to support improved patient care.
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Part of Sepsis Alliance Symposium: Diagnostics and Diagnostic Stewardship 2026
Description:
Timely and accurate diagnosis of sepsis is essential to improving outcomes, yet resource-limited settings face unique challenges, including limited laboratory capacity, delayed testing, workforce constraints, and competing clinical priorities.
This session will examine current and emerging approaches to sepsis diagnostics with an emphasis on diagnostic stewardship in low-resource and under-resourced environments. Participants will explore practical strategies for optimizing the use of available diagnostic tools, such as clinical criteria, basic laboratory tests, microbiology, and point-of-care technologies, while minimizing unnecessary testing and delays in treatment. Context-appropriate algorithms, implementation considerations, and examples from global and rural health settings will also be highlighted. Emphasis will be placed on balancing early sepsis recognition, antimicrobial stewardship, cost-effectiveness, and equitable access to care.
Learning Objectives:
At the end of this session, the learner should be able to:
- Describe key challenges and limitations affecting sepsis diagnosis in resource-limited settings.
- Apply principles of diagnostic stewardship to optimize sepsis evaluation using available clinical and laboratory resources;
- Compare the utility of clinical assessment, basic laboratory testing, microbiology, and point-of-care diagnostics for sepsis in low-resource environments.
- Integrate diagnostic strategies that support timely treatment while minimizing unnecessary testing and inappropriate antimicrobial use.
- Identify practical, scalable approaches to improving sepsis diagnostic pathways in resource-constrained health systems.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
$i++ ?>Michael McCurdy, MD
Clinical Professor of Pulmonary and Critical Care Medicine and Emergency Medicine
University School of Maryland School of Medicine
Michael McCurdy, MD, is a triple-board-certified critical care physician who has used his extensive clinical and research experience to focus on creating, developing, and deploying novel solutions to complex medical problems encountered in the inpatient, outpatient, austere, and military environments. A clinical professor of Pulmonary and Critical Care Medicine and Emergency Medicine at The University of Maryland School of Medicine, Dr. McCurdy has authored over 130 peer-reviewed manuscripts. His clinical research primarily focuses on novel ways to identify and resuscitate sepsis and other shock states, improve acute medical care in austere environments, and provide telemedical ultrasound support to remote clinicians. His work has led to multiple inventions to assist with bedside resuscitation efforts. He serves as an advisor or board member for several companies and nonprofit organizations.
Dr. McCurdy remains involved with Nereus Medical Solutions, which delivers critical care in various austere environments around the globe. While he enjoyed serving as the lone physician providing medical support for a National Geographic around-the-world trip to many of the globe’s most remote regions, hehas focused the bulk of his international efforts on St. Luke’s Hospital in Port-au-Prince, Haiti. His multi-year efforts there centered on educating Haitian physicians to conduct clinical research for the purpose of establishing a long-term, sustainable medical infrastructure that seamlessly integrates low-cost technology and high-quality education and patient care. His hope is that his group’s work will serve generations of Haitians while also providing a framework for the creation of similar sustainable medical care in other resource-limited countries.
Dr. McCurdy previously served as the Chief Medical Officer of BOA Biomedical, utilizing a DARPA-funded pan-pathogen-binding protein developed at Harvard University’s Wyss Institute to enable rapid pathogen identification and clearance. He now serves as the CMO of Clairyon, a University of California San Diego-based AI company focused on deploying: inpatient and outpatient sepsis predictive analytics tools that ingest and process multimodal data sources (e.g., EHR, wearables, symptom assessment tools), automated inpatient quality assessment and reporting, and a generative AI mobile chatbot to streamline the management of illness and predict the development of outpatient clinical decompensation, particularly from sepsis.