From Evidence to Action: Implementing the IPSO Change Package in Real-World Care
Includes a Live Web Event on 04/21/2026 at 8:00 AM (PDT)
Description:
Date: Tuesday, April 21, 2026
Time: 11:00 am - 12:00 pm ET / 8:00 - 9:00 am PT
Sepsis remains a leading cause of morbidity and mortality in children, yet variation in care persists. From 2017 – 2023, the Children’s Hospital Association (CHA) Improving Pediatric Sepsis Outcomes (IPSO) collaborative engaged 66 children’s hospitals in a quality improvement (QI) initiative to reduce sepsis-attributable mortality. Following a learning health systems model, IPSO established and supported the implementation of evidence-based care bundles to improve early recognition and timely treatment of sepsis. Utilizing QI tenets, advanced data analytics, and national collaboration, IPSO’s approach accelerated learning, successfully improving compliance with sepsis care processes, resulting in reduced care disparities, health care utilization, and mortality.
This webinar highlights learnings that were incorporated into the IPSO Change Package as a practical roadmap for teams seeking to improve reliability in sepsis identification, treatment, and follow-up. Attendees will learn how to apply change concepts, test improvements using quality improvement methods, and align multidisciplinary teams around shared goals. The session will also address common implementation challenges and strategies for sustaining gains over time.
Learning Objectives:
At the end of the activity, the learner should be able to:
- Describe the key components of the IPSO Change Package and how they address common sources of variation in pediatric sepsis identification, treatment, and follow‑up care;
- Apply selected change ideas from the Sepsis Change Package to a local context using quality improvement methods to improve reliability of sepsis care;
- Identify strategies for engaging multidisciplinary teams and sustaining improvements in sepsis performance over time.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Sarah Kandil, MD
Associate Professor of Pediatrics at Yale New Haven Children’s Hospital
Yale School of Medicine
Sarah Kandil, MD, is the Deputy Quality and Safety Officer and Associate Professor of Pediatrics at Yale New Haven Children’s Hospital. She served on the IPSO leadership group and research workgroup and is now the Co-Chair (2026) of the Pediatric Sepsis Community of Practice Steering Committee, where she supports national efforts to improve pediatric sepsis care through quality and safety leadership.
Melissa Schafer, MD
Professor of Pediatrics
Upstate Golisano Children’s Hospital
Melissa Schafer, MD, is the Director of Pediatric Hospital Medicine and Professor of Pediatrics at Upstate Golisano Children’s Hospital in Syracuse. She is a member of the Pediatric Sepsis Community of Practice Steering Committee and contributes clinical expertise to advancing sepsis care improvement initiatives.
Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Sepsis Alliance designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Provider approved by the California Board of Registered Nursing, Provider Number CEP17068 for 1.2 contact hours.
Other healthcare professionals will receive a certificate of attendance for 1.0 contact hours.
All individuals in control of content for this activity disclosed no relevant financial relationships.
Medical Disclaimer
The information on or available through this site is intended for educational purposes only. Sepsis Alliance does not represent or guarantee that information on or available through this site is applicable to any specific patient’s care or treatment. The educational content on or available through this site does not constitute medical advice from a physician and is not to be used as a substitute for treatment or advice from a practicing physician or other healthcare professional. Sepsis Alliance recommends users consult their physician or healthcare professional regarding any questions about whether the information on or available through this site might apply to their individual treatment or care.