Description:
Episode 5 of The Sepsis Spectrum: Sepsis and MODS podcast
Acute kidney injury (AKI) is a common but complex component of MODS, with far-reaching effects on fluid balance, acid-base regulation, and overall prognosis. This episode examines how renal dysfunction develops in sepsis, whether from hypoperfusion, inflammatory insult, or nephrotoxicity, and what the kidneys are (or aren’t) doing during the acute phase. We’ll discuss diagnostic markers, renal replacement therapies, and considerations for post-sepsis renal recovery.
Learning Objectives:
At the end of the session, the learner should be able to:
- Explain the primary mechanisms contributing to acute kidney injury (AKI) during sepsis;
- Interpret renal function tests and emerging biomarkers to detect early stages of sepsis-associated AKI;
- Implement evidence-based strategies for fluid management and renal replacement therapy initiation in septic patients;
- Assess the implications of AKI on multi-organ dysfunction and post-sepsis renal recovery.
Target Audience:
Nurses, advanced practice providers, physicians, emergency responders, pharmacists, medical technologists, respiratory therapists, physical/occupational therapists, infection prevention specialists, data/quality specialists, and more.
Guests:
Gonzalo Matzumura, MD
Assistant Professor of Medicine, Division of Nephrology
WashU Medicine
Gonzalo Matzumura Umemoto, MD, is an Assistant Professor of Medicine in the Division of Nephrology at Washington University School of Medicine. He serves as the Director of Acute Dialysis Services at Barnes-Jewish Hospital.
He earned his medical degree in 2007 from Universidad Peruana Cayetano Heredia in Lima, Peru. He completed his residency in Internal Medicine at UTHealth (McGovern Medical School) in Houston (2016) and went on to finish his Nephrology fellowship at Washington University in St. Louis in 2019.
Dr. Matzumura is board-certified in Internal Medicine and Nephrology. His clinical and research interests include acute kidney injury, onconephrology, continuous renal replacement therapy, functional renal imaging, kidney biopsy, and point-of-care ultrasound.
He has received recognition including the “Karen L. Campbell PhD Travel Award” from the American Society of Nephrology and was named Junior Resident of the Year during his internal medicine training.
CE Information:
Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Sepsis Alliance designates this live activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Provider approved by the California Board of Registered Nursing, Provider Number CEP17068 for 0.8 contact hours.
Other healthcare professionals will receive a certificate of attendance for 0.5 contact hours.
Financial Relationship Disclosures:
All individuals in control of content disclosed no relevant financial relationships.
Medical Disclaimer:
The information on or available through this site is intended for educational purposes only. Sepsis Alliance does not represent or guarantee that information on or available through this site is applicable to any specific patient’s care or treatment. The educational content on or available through this site does not constitute medical advice from a physician and is not to be used as a substitute for treatment or advice from a practicing physician or other healthcare professional. Sepsis Alliance recommends users consult their physician or healthcare professional regarding any questions about whether the information on or available through this site might apply to their individual treatment or care.